5-dehydro-4-deoxyglucarate dehydratase

The enzyme 5-dehydro-4-deoxyglucarate dehydratase (Template:EnzExplorer) catalyzes the chemical reaction

5-dehydro-4-deoxy-D-glucarate $\rightleftharpoons$ 2,5-dioxopentanoate + H₂O + CO₂

Enzyme class

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating 2,5-dioxopentanoate-forming). Other names in common use include 5-keto-4-deoxy-glucarate dehydratase, deoxyketoglucarate dehydratase, D-4-deoxy-5-ketoglucarate hydro-lyase, and 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating). This enzyme participates in ascorbate and aldarate metabolism.

References

• Template:Cite journal

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