4-hydroxybenzoate—CoA ligase
Template:Short description Template:Infobox enzyme In enzymology, a 4-hydroxybenzoate—CoA ligase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction
- ATP + 4-hydroxybenzoate + CoA AMP + diphosphate + 4-hydroxybenzoyl-CoA
The 3 substrates of this enzyme are ATP, 4-hydroxybenzoate, and CoA, whereas its 3 products are AMP, diphosphate, and 4-hydroxybenzoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 4-hydroxybenzoate:CoA ligase (AMP-forming). Other names in common use include 4-hydroxybenzoate-CoA synthetase, 4-hydroxybenzoate-coenzyme A ligase (AMP-forming), 4-hydroxybenzoyl coenzyme A synthetase, and 4-hydroxybenzoyl-CoA ligase. This enzyme participates in benzoate degradation via coa ligation.
References
Template:Ligases CO CS and CN Template:Enzymes Template:Portal bar