Indolepyruvate decarboxylase

Template:Infobox enzyme The enzyme indolepyruvate decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction

3-(indol-3-yl)pyruvate $\rightleftharpoons$ 2-(indol-3-yl)acetaldehyde + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]. Other names in common use include indol-3-yl-pyruvate carboxy-lyase, and 3-(indol-3-yl)pyruvate carboxy-lyase. This enzyme participates in tryptophan metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

• Template:Cite journal

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