Arylmalonate decarboxylase

Template:Short description Template:Infobox enzyme The enzyme arylmalonate decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction

2-aryl-2-methylmalonate $\rightleftharpoons$ 2-arylpropanoate + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming). Other names in common use include AMDASE, 2-aryl-2-methylmalonate carboxy-lyase, and 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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