5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Template:Short description Template:Infobox enzyme The enzyme 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction

5-oxopent-3-ene-1,2,5-tricarboxylate $\rightleftharpoons$ 2-oxohept-3-enedioate + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming). Other names in common use include 5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase, and 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase. This enzyme participates in tyrosine metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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