UDP-N-acetylglucosamine 4-epimerase

Template:Short description Template:Infobox enzyme In enzymology, an UDP-N-acetylglucosamine 4-epimerase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine $\rightleftharpoons$ UDP-N-acetyl-D-galactosamine

Hence, this enzyme has one substrate, UDP-N-acetyl-D-glucosamine, and one product, UDP-N-acetyl-D-galactosamine.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine 4-epimerase. Other names in common use include UDP acetylglucosamine epimerase, uridine diphosphoacetylglucosamine epimerase, uridine diphosphate N-acetylglucosamine-4-epimerase, and uridine 5'-diphospho-N-acetylglucosamine-4-epimerase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.

References

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