ADP-glyceromanno-heptose 6-epimerase

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Template:Infobox enzyme In enzymology, an ADP-L-glycero-D-manno-heptose 6-epimerase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction

ADP-D-glycero-D-manno-heptose ADP-L-glycero-D-manno-heptose

Hence, this enzyme has one substrate, ADP-D-glycero-D-manno-heptose, and one product, ADP-L-glycero-D-manno-heptose.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is ADP-L-glycero-D-manno-heptose 6-epimerase. This enzyme participates in lipopolysaccharide biosynthesis. It employs one cofactor, NADP+ in a direct oxidation mechanism.

Structural studies

As of 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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Template:Racemases and epimerases Template:Enzymes Template:Portal bar


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