Pyruvate oxidase (CoA-acetylating)

Template:Technical Template:Infobox enzyme In enzymology, a pyruvate oxidase (CoA-acetylating) (Template:EC number) is an enzyme that catalyzes the chemical reaction

pyruvate + CoA + O₂ $\rightleftharpoons$ acetyl-CoA + CO₂ + H₂O₂

The 3 substrates of this enzyme are pyruvate, CoA, and O₂, whereas its 3 products are acetyl-CoA, CO₂, and H₂O₂.

This enzyme belongs to the family of oxidoreductases , specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyruvate:oxygen 2 - oxidoreductase (CoA-acetylating). This enzyme participates in pyruvate metabolism. It employs one cofactor, FAD.

References

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