4-aminobenzoate 1-monooxygenase

Template:Short description Template:Infobox enzyme In enzymology, a 4-aminobenzoate 1-monooxygenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

4-aminobenzoate + NAD(P)H + 2 H⁺ + O₂ $\rightleftharpoons$ 4-hydroxyaniline + NAD(P)+ + H₂O + CO₂

The 5 substrates of this enzyme are 4-aminobenzoate, NADH, NADPH, H⁺, and O₂, whereas its 5 products are 4-hydroxyaniline, NAD⁺, NADP⁺, H₂O, and CO₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating). Other names in common use include 4-aminobenzoate hydroxylase, and 4-aminobenzoate monooxygenase. This enzyme participates in 2,4-dichlorobenzoate degradation. It employs one cofactor, FAD.

References

• Template:Cite journal

Template:1.14.13-enzyme-stub