2-Coumarate reductase

Template:Short description Template:Infobox enzyme In enzymology, a 2-coumarate reductase or melilotate dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

3-(2-hydroxyphenyl)propanoate + NAD⁺ $\rightleftharpoons$ 2-coumarate + NADH + H⁺

Thus, the two substrates of this enzyme are 3-(2-hydroxyphenyl)propanoate and NAD⁺, whereas its 3 products are 2-coumarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme participates in phenylalanine metabolism.

References

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