(R)-2-hydroxy-fatty-acid dehydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a (R)-2-hydroxy-fatty-acid dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

(R)-2-hydroxystearate + NADTemplate:Sup $\rightleftharpoons$ 2-oxostearate + NADH + HTemplate:Sup

Thus, the two substrates of this enzyme are (R)-2-hydroxystearate and [[nicotinamide adenine dinucleotide|NADTemplate:Sup]], whereas its 3 products are 2-oxostearate, NADH, and [[hydrogen ion|HTemplate:Sup]]. This reaction is important in fatty acid metabolism.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NADTemplate:Sup or NADPTemplate:Sup as acceptor. The systematic name of this enzyme class is (R)-2-hydroxystearate:NADTemplate:Sup oxidoreductase. Other names in common use include D-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.

References

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