16-alpha-hydroxysteroid dehydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a 16alpha-hydroxysteroid dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

a 16alpha-hydroxysteroid + NAD(P)⁺ $\rightleftharpoons$ a 16-oxosteroid + NAD(P)H + H⁺

The 3 substrates of this enzyme are 16alpha-hydroxysteroid, NAD⁺, and NADP⁺, whereas its 4 products are 16-oxosteroid, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 16alpha-hydroxysteroid:NAD(P)⁺ 16-oxidoreductase. This enzyme is also called 16alpha-hydroxy steroid dehydrogenase.

References

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