Glucose 1-dehydrogenase

Template:Other uses Template:Infobox enzyme In enzymology, a glucose 1-dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

beta-D-glucose + NAD(P)⁺ $\rightleftharpoons$ D-glucono-1,5-lactone + NAD(P)H + H⁺

The 3 substrates of this enzyme are beta-D-glucose, NAD⁺, and NADP⁺, whereas its 4 products are D-glucono-1,5-lactone, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is beta-D-glucose:NAD(P)⁺ 1-oxidoreductase. Another name in common use is D-glucose dehydrogenase (NAD(P)⁺).

Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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