ADP-dependent NAD(P)H-hydrate dehydratase

Template:Infobox enzyme ADP-dependent NAD(P)H-hydrate dehydratase (Template:EnzExplorer, (6S)-β-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing), (6S)-6-β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing, NADH-forming)) is an enzyme with systematic name (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing; NADH-forming). This enzyme catalyses the following chemical reaction

(1) ADP + (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide $\rightleftharpoons$ AMP + phosphate + NADH

(2) ADP + (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate $\rightleftharpoons$ AMP + phosphate + NADPH

This enzyme acts equally well on hydrated NADH and hydrated NADPH.

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