Hypoxia-inducible factor-asparagine dioxygenase: Difference between revisions

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Latest revision as of 15:31, 26 August 2023

Template:Infobox enzyme Hypoxia-inducible factor-asparagine dioxygenase (Template:EC number, HIF hydroxylase) is an enzyme with systematic name hypoxia-inducible factor-L-asparagine, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction:

hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O2 hypoxia-inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO2

Hypoxia-inducible factor-asparagine dioxygenase contains iron, and requires ascorbate.

References

Template:Reflist

Template:Dioxygenases Template:Enzymes Template:Portal bar