Glycerol 2-dehydrogenase (NADP+)

Template:Infobox enzyme In enzymology, a glycerol 2-dehydrogenase (NADP⁺) (Template:EC number) is an enzyme that catalyzes the chemical reaction

glycerol + NADP⁺ $\rightleftharpoons$ glycerone + NADPH + H⁺

Thus, the two substrates of this enzyme are glycerol and NADP⁺, whereas its 3 products are glycerone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is glycerol:NADP⁺ 2-oxidoreductase (glycerone-forming). Other names in common use include dihydroxyacetone reductase, dihydroxyacetone (reduced nicotinamide adenine dinucleotide, phosphate) reductase, dihydroxyacetone reductase (NADPH), DHA oxidoreductase, and glycerol 2-dehydrogenase (NADP⁺). This enzyme participates in glycerolipid metabolism.

References

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