View source for Tetrahydromethanopterin S-methyltransferase

{{infobox enzyme
| Name       = tetrahydromethanopterin S-methyltransferase
| EC_number  = 2.1.1.86
| CAS_number = 103406-60-6
| GO_code    = 0030269
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], a '''tetrahydromethanopterin S-methyltransferase''' ({{EC number|2.1.1.86}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate <math>\rightleftharpoons</math> 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[5-methyl-5,6,7,8-tetrahydromethanopterin]] and [[2-mercaptoethanesulfonate]] (coenzyme M), whereas its two [[product (chemistry)|products]] are [[5,6,7,8-tetrahydromethanopterin]] and [[2-(methylthio)ethanesulfonate]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases.  The [[List of enzymes|systematic name]] of this enzyme class is '''5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase'''. This enzyme is also called '''tetrahydromethanopterin methyltransferase'''.  This enzyme participates in [[folate biosynthesis]].

== References ==
{{reflist|1}}
* {{cite journal | vauthors = Sauer FD | title = Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum | journal = Biochemical and Biophysical Research Communications | volume = 136 | issue = 2 | pages = 542–7 | date = April 1986 | pmid = 3085670 | doi = 10.1016/0006-291X(86)90474-2 }}

{{One carbon transferases}}
{{Enzymes}}
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[[Category:EC 2.1.1]]
[[Category:Enzymes of unknown structure]]


{{2.1-enzyme-stub}}