View source for Serine 3-dehydrogenase

{{infobox enzyme
| Name       = serine 3-dehydrogenase
| EC_number  = 1.1.1.276
| CAS_number = 9038-55-5
| GO_code    = 0031132
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], a '''serine 3-dehydrogenase''' ({{EC number|1.1.1.276}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:L-serine + NADP<sup>+</sup> <math>\rightleftharpoons</math> 2-ammoniomalonate semialdehyde + NADPH + H<sup>+</sup>

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-serine]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[2-ammoniomalonate semialdehyde]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is '''L-serine:NADP<sup>+</sup> 3-oxidoreductase'''.

==References==
{{reflist|1}}
* {{cite journal | vauthors = Fujisawa H, Nagata S, Chowdhury EK, Matsumoto M, Misono H | date = 2002 | title = Cloning and sequencing of the serine dehydrogenase gene from ''Agrobacterium tumefaciens'' | journal = Biosci. Biotechnol. Biochem. | volume = 66 | pages = 1137&ndash;9 | pmid = 12092831 | doi = 10.1271/bbb.66.1137 | issue = 5 | doi-access = free }}
* {{cite journal | vauthors = Chowdhury EK, Higuchi K, Nagata S, Misono H | date = 1997 | title = A novel NADP(+)-dependent serine dehydrogenase from ''Agrobacterium tumefaciens'' | journal = Biosci. Biotechnol. Biochem. | volume = 61 | pages = 152&ndash;7 | pmid = 9028042 | doi = 10.1271/bbb.61.152 | issue = 1 | doi-access = free }}

{{Alcohol oxidoreductases}}
{{Enzymes}}
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[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]


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