View source for Pyridoxine 5-dehydrogenase

{{infobox enzyme
| Name       = pyridoxine 5-dehydrogenase
| EC_number  = 1.1.99.9
| CAS_number = 9023-39-6
| GO_code    = 0050238
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], a '''pyridoxine 5-dehydrogenase''' ({{EC number|1.1.99.9}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:pyridoxine + acceptor <math>\rightleftharpoons</math> isopyridoxal + reduced acceptor

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[pyridoxine]] and [[Electron acceptor|acceptor]], whereas its two [[product (chemistry)|products]] are [[isopyridoxal]] and [[reduced acceptor]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with other acceptors.  The [[List of enzymes|systematic name]] of this enzyme class is '''pyridoxine:acceptor 5-oxidoreductase'''. Other names in common use include '''pyridoxal-5-dehydrogenase''', '''pyridoxol 5-dehydrogenase''', '''pyridoxin 5-dehydrogenase''', '''pyridoxine dehydrogenase''', '''pyridoxine 5'-dehydrogenase''', and '''pyridoxine:(acceptor) 5-oxidoreductase'''.  This enzyme participates in [[vitamin B6|vitamin B<sub>6</sub> metabolism]].  It has 2 [[cofactor (biochemistry)|cofactors]]: [[flavin adenine dinucleotide|FAD]],  and [[Pyrroloquinoline quinone|PQQ]].

==References==
{{reflist|1}}
* {{cite journal | vauthors = Sundaram TK, Snell EE | date = 1969 | title = The bacterial oxidation of vitamin B6. V. The enzymatic formation of pyridoxal and isopyridoxal from pyridoxine | journal = J. Biol. Chem.  | volume = 244 | pages = 2577&ndash;84  | pmid = 5769992 | issue = 10 | doi = 10.1016/S0021-9258(18)83439-1 | doi-access = free }}

{{Alcohol oxidoreductases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}

[[Category:EC 1.1.99]]
[[Category:Flavoproteins]]
[[Category:Pyrroloquinoline quinone enzymes]]
[[Category:Enzymes of unknown structure]]


{{1.1-enzyme-stub}}