View source for Phosphonopyruvate decarboxylase

{{infobox enzyme
| Name       = Phosphonopyruvate decarboxylase
| EC_number  = 4.1.1.82
| CAS_number =
| GO_code    = 
| image      = PnPy_to_PnAA.png
| caption = A reaction using Ppd as a catalyst
| width      = 
}}
The [[enzyme]] '''phosphonopyruvate decarboxylase''' ({{EnzExplorer|4.1.1.82}}) [[catalysis|catalyzes]] the [[chemical reaction]]

:3-phosphonopyruvate <math>\rightleftharpoons</math> 2-phosphonoacetaldehyde + CO<sub>2</sub>

This enzyme belongs to the family of [[lyase]]s, specifically the carboxy-lyases, which cleave carbon-carbon bonds.  The [[List of enzymes|systematic name]] of this enzyme class is '''3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming)'''. This enzyme is also called '''3-phosphonopyruvate carboxy-lyase'''.  This enzyme participates in [[aminophosphonate metabolism]].

==References==
{{reflist|1}}
* {{cite journal | vauthors = Zhang G, Dai J, Lu Z, Dunaway-Mariano D | date = 2003 | title = The phosphonopyruvate decarboxylase from Bacteroides fragilis | journal = J. Biol. Chem.  | volume = 278 | pages = 41302&ndash;8  | pmid = 12904299 | doi = 10.1074/jbc.M305976200 | issue = 42 | doi-access = free }}
* {{cite journal | vauthors = Seidel HM, Knowles JR | date = 1994 | title = Interaction of inhibitors with phosphoenolpyruvate mutase: implications for the reaction mechanism and the nature of the active site | journal = Biochemistry  | volume = 33 | pages = 5641&ndash;6  | pmid = 8180189 | doi = 10.1021/bi00184a037 | issue = 18 }}
* {{cite journal | vauthors = Nakashita H, Watanabe K, Hara O, Hidaka T, Seto H | location = Tokyo | title = Studies on the biosynthesis of bialaphos. Biochemical mechanism of C-P bond formation: discovery of phosphonopyruvate decarboxylase which catalyzes the formation of phosphonoacetaldehyde from phosphonopyruvate | journal = J. Antibiot. | pages = 212&ndash;9  | pmid = 9127192 | issue = 3 | volume=50 | date=March 1997 | doi=10.7164/antibiotics.50.212| doi-access = free }}

{{Carbon-carbon lyases}}
{{Enzymes}}
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[[Category:EC 4.1.1]]
[[Category:Enzymes of unknown structure]]


{{4.1-enzyme-stub}}