View source for O-phospho-L-seryl-tRNA:Cys-tRNA synthase

{{Infobox enzyme
| Name       = O-phospho-L-seryl-tRNA:Cys-tRNA synthase
| EC_number  = 2.5.1.73
| CAS_number = 1239229-21-0
| GO_code    =
| image      = 
| width      = 
| caption    =  
}}
'''O-phospho-L-seryl-tRNA:Cys-tRNA synthase''' ({{EC number|2.5.1.73}}, ''SepCysS'', ''Sep-tRNA:Cys-tRNA synthase'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''O-phospho-L-seryl-tRNACys:[[hydrogen sulfide]] 2-aminopropanoate transferase''.<ref>{{cite journal | vauthors = Fukunaga R, Yokoyama S | title = Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus | journal = Journal of Molecular Biology | volume = 370 | issue = 1 | pages = 128–41 | date = June 2007 | pmid = 17512006 | doi = 10.1016/j.jmb.2007.04.050 }}</ref><ref>{{cite journal | vauthors = Hauenstein SI, Perona JJ | title = Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei | journal = The Journal of Biological Chemistry | volume = 283 | issue = 32 | pages = 22007–17 | date = August 2008 | pmid = 18559341 | pmc = 2494925 | doi = 10.1074/jbc.M801839200 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Yuan J, Palioura S, Salazar JC, Su D, O'Donoghue P, Hohn MJ, Cardoso AM, Whitman WB, Söll D | title = RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 50 | pages = 18923–7 | date = December 2006 | pmid = 17142313 | pmc = 1748153 | doi = 10.1073/pnas.0609703104 | bibcode = 2006PNAS..10318923Y | doi-access = free }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: O-phospho-L-seryl-tRNACys + [[sulfide]] <math>\rightleftharpoons</math> L-cysteinyl-tRNACys + [[phosphate]]

== References ==
{{reflist}}

== External links ==
* {{MeshName|O-phospho-L-seryl-tRNA:Cys-tRNA+synthase}}

{{Alkyl and aryl transferases}}
{{Enzymes}}
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[[Category:EC 2.5.1]]