View source for Myristoyl-CoA 11-(Z) desaturase

{{infobox enzyme
| Name       = myristoyl-CoA 11-(Z) desaturase
| EC_number  = 1.14.99.32
| CAS_number =
| GO_code    = 0050601
| image      = 
| width      = 
| caption    =  
}}
In [[enzymology]], a '''myristoyl-CoA 11-(Z) desaturase''' ({{EC number|1.14.99.32}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:myristoyl-CoA + NAD(P)H + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H<sub>2</sub>O

The 5 [[substrate (biochemistry)|substrates]] of this enzyme are [[myristoyl-CoA]], [[nicotinamide adenine dinucleotide|NADH]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], [[hydrogen ion|H<sup>+</sup>]], and [[oxygen|O<sub>2</sub>]], whereas its 4 [[product (chemistry)|products]] are [[(Z)-11-tetradecenoyl-CoA]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous.  The [[List of enzymes|systematic name]] of this enzyme class is '''n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]'''. This enzyme is also called '''n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]'''.

==References==
{{reflist|1}}
* {{cite journal | vauthors = Navaro I, Font I, Fabrias G, Camps F | date = 1997 | title = Stereospecificity of the (E)- and (Z)-11 myristoyl desaturases in the biosynthesis of Spodoptera littoralis sex pheromone | journal = J. Am. Chem. Soc.  | volume = 119 | pages = 11335&ndash;11336 | doi = 10.1021/ja972577v | issue = 46 }}

{{Dioxygenases}}
{{Enzymes}}
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[[Category:EC 1.14.99]]
[[Category:NADPH-dependent enzymes]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]


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