View source for Linoleate 10R-lipoxygenase

{{Infobox enzyme
| Name       = Linoleate 10R-lipoxygenase
| EC_number  = 1.13.11.62
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''Linoleate 10R-lipoxygenase''' ({{EC number|1.13.11.62}}, ''10R-DOX'', ''(10R)-dioxygenase'', ''10R-dioxygenase'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''linoleate:oxygen (10R)-oxidoreductase''.<ref>{{cite journal | vauthors = Garscha U, Oliw EH | title = Leucine/valine residues direct oxygenation of linoleic acid by (10R)- and (8R)-dioxygenases: expression and site-directed mutagenesis oF (10R)-dioxygenase with epoxyalcohol synthase activity | journal = The Journal of Biological Chemistry | volume = 284 | issue = 20 | pages = 13755–65 | date = May 2009 | pmid = 19289462 | pmc = 2679477 | doi = 10.1074/jbc.M808665200 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Jernerén F, Garscha U, Hoffmann I, Hamberg M, Oliw EH | title = Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus | journal = Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | volume = 1801 | issue = 4 | pages = 503–7 | date = April 2010 | pmid = 20045744 | doi = 10.1016/j.bbalip.2009.12.012 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: linoleate + O<sub>2</sub> <math>\rightleftharpoons</math> (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate

Linoleate 10R-lipoxygenase is involved in biosynthesis of [[oxylipins]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Linoleate+10R-lipoxygenase}}

{{Monooxygenases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}

[[Category:EC 1.13.11]]