View source for Inositol 1-methyltransferase

{{infobox enzyme
| Name       = inositol 1-methyltransferase
| EC_number  = 2.1.1.40
| CAS_number = 37257-06-0
| GO_code    = 0030741
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], an '''inositol 1-methyltransferase''' ({{EC number|2.1.1.40}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:S-adenosyl-L-methionine + myo-inositol <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 1D-1-O-methyl-myo-inositol

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[myo-inositol]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[1D-1-O-methyl-myo-inositol]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases.  The [[List of enzymes|systematic name]] of this enzyme class is '''S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase'''. Other names in common use include '''inositol D-1-methyltransferase''', '''S-adenosylmethionine:myo-inositol 3-methyltransferase''', '''myo-inositol 3-O-methyltransferase''', '''inositol 3-O-methyltransferase (name based on 1L-numbering system''', '''and not 1D-numbering)''', and '''S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase'''.  This enzyme participates in [[inositol phosphate metabolism]].

==References==
{{reflist|1}}
* {{cite journal |vauthors=Wagner I, Hofmann H, Hoffmann-Ostenhof O | date = 1969 | title = [Biosynthesis of cyclitols. 23. A soluble enzyme from pea seedlings methylating myo-inositol to D-bornesitol] | journal = Hoppe-Seyler's Z. Physiol. Chem.  | volume = 350 | pages = 1460&ndash;4  | pmid = 5362620 | issue = 11 }}

{{One carbon transferases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}

[[Category:EC 2.1.1]]
[[Category:Enzymes of unknown structure]]
[[Category:Inositol]]


{{2.1-enzyme-stub}}