View source for Glycerophospholipid acyltransferase (CoA-dependent)

{{infobox enzyme
| Name       = glycerophospholipid acyltransferase (CoA-dependent)
| EC_number  = 2.3.1.148
| CAS_number = 9054-54-0
| GO_code    = 0047178
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], a '''glycerophospholipid acyltransferase (CoA-dependent)''' ({{EC number|2.3.1.148}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:1-organyl-2-acyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine <math>\rightleftharpoons</math> 1-organyl-2-acyl-sn-glycero-3-phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[1-organyl-2-acyl-sn-glycero-3-phosphocholine]] and [[1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine]], whereas its two [[product (chemistry)|products]] are [[1-organyl-2-acyl-sn-glycero-3-phosphoethanolamine]] and [[1-organyl-2-lyso-sn-glycero-3-phosphocholine]].

This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.  The [[List of enzymes|systematic name]] of this enzyme class is '''1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-gly cero-3-phosphoethanolamine acyltransferase (CoA-dependent)'''.

==References==
{{reflist|1}}
* {{cite journal | vauthors = Irvine RF, Dawson RM | date = 1979 | title = Transfer of arachidonic acid between phospholipids in rat liver microsomes | journal = Biochem. Biophys. Res. Commun.  | volume = 91 | pages = 1399&ndash;405  | pmid = 526311 | doi = 10.1016/0006-291X(79)91222-1 | issue = 4 }}
* {{cite journal | vauthors = Robinson M, Blank ML, Snyder F | date = 1985 | title = Acylation of lysophospholipids by rabbit alveolar macrophages Specificities of CoA-dependent and CoA-independent reactions | journal = J. Biol. Chem.  | volume = 260 | pages = 7889&ndash;95  | pmid = 4008481 | issue = 13 }}
* {{cite journal | vauthors = Snyder F, Lee TC, Blank ML | date = 1992 | title = The role of transacylases in the metabolism of arachidonate and platelet activating factor | journal = Prog. Lipid Res.  | volume = 31 | pages = 65&ndash;86  | pmid = 1641397 | doi = 10.1016/0163-7827(92)90016-C | issue = 1 | url = https://zenodo.org/record/1258345 }}

{{Acyltransferases}}
{{Enzymes}}
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[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]


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