View source for Gellan tetrasaccharide unsaturated glucuronyl hydrolase

{{Infobox enzyme
| Name       = Gellan tetrasaccharide unsaturated glucuronyl hydrolase
| EC_number  = 3.2.1.179
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''Gellan tetrasaccharide unsaturated glucuronyl hydrolase''' ({{EC number|3.2.1.179}}, ''UGL'', ''unsaturated glucuronyl hydrolase'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''beta-D-4-deoxy-Delta4-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp beta-D-4-deoxy-Delta4-GlcAp hydrolase''.<ref>{{cite journal | vauthors = Itoh T, Akao S, Hashimoto W, Mikami B, Murata K | title = Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution | journal = The Journal of Biological Chemistry | volume = 279 | issue = 30 | pages = 31804–12 | date = July 2004 | pmid = 15148314 | doi = 10.1074/jbc.m403288200 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K | title = Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases | journal = Archives of Biochemistry and Biophysics | volume = 368 | issue = 2 | pages = 367–74 | date = August 1999 | pmid = 10441389 | doi = 10.1006/abbi.1999.1305 }}</ref><ref>{{cite journal | vauthors = Itoh T, Hashimoto W, Mikami B, Murata K | title = Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1 | journal = Biochemical and Biophysical Research Communications | volume = 344 | issue = 1 | pages = 253–62 | date = May 2006 | pmid = 16630576 | doi = 10.1016/j.bbrc.2006.03.141 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: beta-D-4-deoxy-Delta4-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp + H<sub>2</sub>O <math>\rightleftharpoons</math> 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp

The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from [[oligosaccharide]]s produced by [[polysaccharide lyase]]s.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Gellan+tetrasaccharide+unsaturated+glucuronyl+hydrolase}}

{{Sugar hydrolases}}
{{Enzymes}}
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[[Category:EC 3.2.1]]