View source for Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide b-1,6-N-acetylglucosaminyltransferase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase
| EC_number  = 2.4.1.164
| CAS_number = 85638-40-0
| GO_code    =
| image      = 
| width      = 
| caption    =  
}}
'''Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase''' ({{EC number|2.4.1.164}}, ''uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase'', ''UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''UDP-N-acetyl-D-glucosamine:D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 6-beta-N-acetylglucosaminyltransferase''.<ref>{{cite journal | vauthors = Basu M, Basu S | title = Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by beta 1-3- and beta 1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma | journal = The Journal of Biological Chemistry | volume = 259 | issue = 20 | pages = 12557–62 | date = October 1984 | pmid = 6238026 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[UDP-N-acetyl-D-glucosamine]] + D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <math>\rightleftharpoons</math> UDP + N-acetyl-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

This enzyme requires Mn<sup>2+</sup>.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide+beta-1,6-N-acetylglucosaminyltransferase}}

{{Glycosyltransferases}}
{{Enzymes}}
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[[Category:EC 2.4.1]]