View source for Ferric-chelate reductase (NADPH)

{{Infobox enzyme
| Name       = Ferric-chelate reductase (NADPH)
| EC_number  = 1.16.1.9
| CAS_number = 120720-17-4
| GO_code    =
| image      = 
| width      = 
| caption    =  
}}
'''Ferric-chelate reductase (NADPH)''' ({{EC number|1.16.1.9}}, ''ferric chelate reductase'', ''iron chelate reductase'', ''NADPH:Fe<sup>3+</sup>-EDTA reductase'', ''NADPH-dependent ferric reductase'', ''yqjH (gene)'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''Fe(II):NADP<sup>+</sup> oxidoreductase''.<ref>{{cite journal | vauthors = Bamford VA, Armour M, Mitchell SA, Cartron M, Andrews SC, Watson KA | title = Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase | journal = Acta Crystallographica Section F | volume = 64 | issue = Pt 9 | pages = 792–6 | date = September 2008 | pmid = 18765906 | pmc = 2531270 | doi = 10.1107/S174430910802352X }}</ref><ref>{{cite journal | vauthors = Wang S, Wu Y, Outten FW | title = Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli | journal = Journal of Bacteriology | volume = 193 | issue = 2 | pages = 563–74 | date = January 2011 | pmid = 21097627 | pmc = 3019823 | doi = 10.1128/JB.01062-10 }}</ref><ref>{{cite journal | vauthors = Miethke M, Hou J, Marahiel MA | title = The siderophore-interacting protein YqjH acts as a ferric reductase in different iron assimilation pathways of Escherichia coli | journal = Biochemistry | volume = 50 | issue = 50 | pages = 10951–64 | date = December 2011 | pmid = 22098718 | doi = 10.1021/bi201517h }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: 2 Fe(II) + 2 apo-siderophore + NADP<sup>+</sup> + H<sup>+</sup> <math>\rightleftharpoons</math> 2 Fe(III)-siderophore + NADPH

Ferric-chelate reductase contains FAD.

== See also ==
* [[Ferric-chelate reductase]]

== References ==
{{reflist}}

== External links ==
* {{MeshName|Ferric-chelate+reductase+(NADPH)}}

{{Other oxidoreductases}}
{{Enzymes}}
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[[Category:EC 1.16.1]]