View source for Cyclohexane-1,2-diol dehydrogenase

{{infobox enzyme
| Name       = cyclohexane-1,2-diol dehydrogenase
| EC_number  = 1.1.1.174
| CAS_number = 62628-27-7
| GO_code    = 0047795
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], a '''cyclohexane-1,2-diol dehydrogenase''' ({{EC number|1.1.1.174}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:trans-cyclohexane-1,2-diol + NAD<sup>+</sup> <math>\rightleftharpoons</math> 2-hydroxycyclohexan-1-one + NADH + H<sup>+</sup>

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[trans-cyclohexane-1,2-diol]] and [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[2-hydroxycyclohexan-1-one]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H<sup>+</sup>]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is '''trans-cyclohexane-1,2-diol:NAD<sup>+</sup> 1-oxidoreductase'''. This enzyme participates in [[caprolactam degradation]].

==References==
{{reflist|1}}
* {{cite journal |vauthors=Davey JF, Trudgill PW | date = 1977 | title = The metabolism of trans-cyclohexan-1,2-diol by an ''Acinetobacter'' species | journal = Eur. J. Biochem. | volume = 74 | pages = 115&ndash;27 | pmid = 856571 | doi = 10.1111/j.1432-1033.1977.tb11373.x | issue = 1 | doi-access = free }}

{{Alcohol oxidoreductases}}
{{Enzymes}}
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[[Category:EC 1.1.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]


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