View source for Asparagine—oxo-acid transaminase

{{infobox enzyme
| Name       = asparagine-oxo-acid transaminase
| EC_number  = 2.6.1.14
| CAS_number = 9030-43-7
| GO_code    = 0047297
| image      =
| width      = 
| caption    =  
}}
In [[enzymology]], an '''asparagine-oxo-acid transaminase''' ({{EC number|2.6.1.14}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:L-asparagine + a 2-oxo acid <math>\rightleftharpoons</math> 2-oxosuccinamate + an amino acid

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-asparagine]] and [[2-oxo acid]], whereas its two [[product (chemistry)|products]] are [[2-oxosuccinamate]] and [[amino acid]].

This enzyme belongs to the family of [[transferase]]s, specifically the [[transaminases]], which transfer nitrogenous groups.  The [[List of enzymes|systematic name]] of this enzyme class is '''L-asparagine:2-oxo-acid aminotransferase'''. This enzyme is also called '''asparagine-keto acid aminotransferase'''.  This enzyme participates in [[alanine and aspartate metabolism]] and [[tetracycline biosynthesis]].  It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]].

==References==
{{reflist|1}}
* {{cite journal |vauthors=MEISTER A, FRASER PE | year = 1954 | title = Enzymatic formation of L-asparagine by transamination | journal = J. Biol. Chem.  | volume = 210 | pages = 37&ndash;43  | pmid = 13201567 | issue = 1 | doi = 10.1016/S0021-9258(18)65430-4 | doi-access = free }}

{{Nitrogenous transferases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}

{{DEFAULTSORT:Asparagine-oxo-acid transaminase}}
[[Category:EC 2.6.1]]
[[Category:Pyridoxal phosphate enzymes]]
[[Category:Enzymes of unknown structure]]


{{2.6-enzyme-stub}}