View source for (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase
| EC_number  = 3.1.3.52
| CAS_number = 87244-20-0, 88086-29-7
| GO_code    =
| image      = 
| width      = 
| caption    =  
}}
'''(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase''' (EC 3.1.3.52, '''branched-chain oxo-acid dehydrogenase phosphatase, branched-chain 2-keto acid dehydrogenase phosphatase, branched-chain α-keto acid dehydrogenase phosphatase, BCKDH', [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase, [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphate phosphohydrolase''') is an [[enzyme]] with [[List of enzymes|systematic name]] '''(3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphate phosphohydrolase'''.<ref>{{cite journal | vauthors = Fatania HR, Patston PA, Randle PJ | title = Dephosphorylation and reactivation of phosphorylated purified ox-kidney branched-chain dehydrogenase complex by co-purified phosphatase | journal = FEBS Letters | volume = 158 | issue = 2 | pages = 234–8 | date = July 1983 | pmid = 6307746 | doi = 10.1016/0014-5793(83)80585-7 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Reed LJ, Damuni Z, Merryfield ML | title = Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation | journal = Current Topics in Cellular Regulation | volume = 27 | pages = 41–9 | year = 1985 | pmid = 3004826 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] + [[phosphate]]

This [[mitochondria]]l enzyme is associated with the [[3-methyl-2-oxobutanoate dehydrogenase]] complex.

== References ==
{{reflist}}

== External links ==
* {{MeshName|(3-methyl-2-oxobutanoate+dehydrogenase+(2-methylpropanoyl-transferring))-phosphatase}}

{{Esterases}}
{{Enzymes}}
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[[Category:EC 3.1.3]]